Masanan kimiyyar Amurka sun yi nazari kan tsarin nazarin halittu da ke bayan kona kitse, sun gano wani sinadarin gina jiki da ke taka muhimmiyar rawa wajen daidaita metabolism, kuma sun tabbatar da cewa toshe ayyukansa na iya inganta wannan tsari a cikin beraye. Ana samar da wannan furotin mai suna Them1 a cikin kitsen ɗan adam mai launin ruwan kasa, wanda ke ba da sabon alkibla ga masu bincike don neman ƙarin ingantattun magunguna don kiba.

Masana kimiyya da ke bayan wannan sabon binciken sun shafe kimanin shekaru goma suna nazarin Them1, kuma suna sha'awar yadda beraye ke samar da adadi mai yawa na furotin a cikin adipose nasu mai launin ruwan kasa a karkashin yanayin sanyi. Ba kamar farin adipose nama wanda ke adana kuzarin da ya wuce kima a cikin jiki a matsayin lipids, ƙwayar adipose mai launin ruwan kasa tana saurin ƙonewa da jiki don haifar da zafi lokacin da muke sanyi. Don haka, yawancin binciken da aka yi na hana kiba sun mayar da hankali kan ƙoƙarin canza kitse mai launin fata zuwa mai launin ruwan kasa.

Masu bincike suna fatan haɓaka gwaje-gwajen bisa waɗannan binciken farko na linzamin kwamfuta wanda aka gyara ƙwayoyin berayen don rashin Them1. Domin sun dauka cewa Them1 yana taimakawa beraye su samar da zafi, suna tsammanin buga shi zai rage musu ikon yin hakan. Amma ya bayyana cewa akasin haka, berayen da ba su da wannan furotin suna cinye makamashi mai yawa don samar da adadin kuzari, ta yadda a zahiri sun ninka mice na yau da kullun, amma har yanzu suna rasa nauyi.

Koyaya, lokacin da kuka goge kwayar halittar Them1, linzamin kwamfuta zai haifar da ƙarin zafi, ba ƙasa ba.

A cikin sabon binciken da aka buga, masana kimiyya sun zurfafa bincike kan dalilan da suka haifar da wannan lamari na bazata. Wannan ya ƙunshi a zahiri lura da tasirin Them1 akan ƙwayoyin kitse mai launin ruwan kasa waɗanda aka girma a cikin dakin gwaje-gwaje ta amfani da na'urorin haske da na lantarki. Wannan yana nuna cewa yayin da kitse ya fara ƙonewa, ƙwayoyin na Them1 suna samun sauye-sauyen sinadarai, wanda ke sa su yaduwa cikin tantanin halitta.

Ɗaya daga cikin illolin wannan yaɗuwar shine cewa mitochondria, wanda aka fi sani da haɓakar tantanin halitta, sun fi iya juyar da ajiyar mai zuwa makamashi. Da zarar mai kona kuzari ya daina, furotin Them1 zai sake tsarawa cikin sauri zuwa tsarin da ke tsakanin mitochondria da mai, yana sake iyakance samar da kuzari.

Hoto mai girma yana nuna: sunadaran sunadaran Them1 a cikin nau'in adipose mai launin ruwan kasa, wanda aka tsara a cikin tsarin da ke hana ƙona makamashi.

Wannan binciken ya bayyana sabon tsarin da ke daidaita metabolism. Them1 yana kai hari kan bututun makamashi kuma yana yanke wadatar mai ga mitochondria mai ƙonewa makamashi. Hakanan mutane suna da kitse mai launin ruwan kasa, wanda zai samar da ƙarin Them1 a ƙarƙashin yanayin sanyi, don haka waɗannan binciken na iya samun tasiri mai ban sha'awa ga maganin kiba.