Ngokutsho kwephepha elitsha elipapashwe kwiSayensi yeKhemikhali, i-prodrug yomlomo eyenziwe liqela lezenzululwazi ekhokelwa nguNjingalwazi uWang Binghe kwiSebe leKhemistry kwiYunivesithi yaseGeorgia State inokubonelela nge-carbon monoxide ukukhusela ukulimala kwezintso.

Nangona i-carbon monoxide (CO) igesi inetyhefu kwiidosi ezinkulu, izazinzulu ziye zafumanisa ukuba zinokuba nemiphumo emihle ngokunciphisa ukuvuvukala kunye nokukhusela iiseli emonakalweni. Uphononongo lwangaphambili lubonise ukuba i-CO inefuthe elikhuselayo kumonakalo wamalungu afana nezintso, imiphunga, i-gastrointestinal tract kunye nesibindi. Kwiminyaka emihlanu edlulileyo, u-Wang kunye nabasebenzisana naye baye basebenza ekuyileni indlela ekhuselekileyo yokuhambisa i-CO kwizigulane zabantu ngokusebenzisa i-prodrugs-inactive compounds ekufuneka iqhube inkqubo yeekhemikhali emzimbeni ngaphambi kokukhulula i-agent esebenzayo ye-pharmacological.