Iingcali zenzululwazi ziye zafumanisa indlela yokulawula ufuzo oluninzi kwiiseli zegwele ezinobunjineli, ukuvula umnyango wemveliso esebenzayo kunye nezinzileyo yeemveliso ezisekelwe kwi-bio.
Uphando lupapashwe kwiNucleic Acids Research ngabaphandi be-DSM's Rosalind Franklin Biotechnology Centre eDelft, eNetherlands kunye neYunivesithi yaseBristol. Uphando lubonisa indlela yokuvula amandla e-CRISPR ukulawula iigene ezininzi ngaxeshanye.
Igwele lika-Baker, okanye igama elipheleleyo elinikwe yi-Saccharomyces cerevisiae, lithathwa njengelona gunya liphambili kwi-biotechnology. Kangangamawaka eminyaka, ibingasetyenziswanga nje ekuveliseni isonka nebhiya, kodwa namhlanje isekwanokwenziwa ukuvelisa uthotho lwezinye iikhompawundi eziluncedo ezisisiseko samayeza, izibaso, nezongezo zokutya. Nangona kunjalo, kunzima ukufezekisa imveliso efanelekileyo yezi mveliso. Kuyimfuneko ukuphinda udibanise kunye nokwandisa inethiwekhi ye-biochemical eyinkimbinkimbi ngaphakathi kwiseli ngokuzisa i-enzymes entsha kunye nokulungelelanisa amanqanaba e-gene expression.
