I-ACE-031peptide iye yaphuhliswa ukunceda ukuphatha ubuthathaka bemisipha kunye nokuwohloka, kwaye i-ACE-031 peptide yiprotheni ye-myostatin-inhibiting eveliswa ukulinganisa i-receptor yendalo echaphazelekayo ekulawuleni ubunzima bemisipha, amandla kunye nomsebenzi.

Intshayelelo yeMveliso:

I-ACE-031peptide iye yaphuhliswa ukunceda ukuphatha ubuthathaka bemisipha kunye nokuwohloka, kwaye i-ACE-031 peptide yiprotheni ye-myostatin-inhibiting eveliswa ukulinganisa i-receptor yendalo echaphazelekayo ekulawuleni ubunzima bemisipha, amandla kunye nomsebenzi. I-ACE-031 isebenza njenge-blocker ye-mysotatin ngokubopha i-myostatin kunye neeprotheni ezongezelelweyo ezilawula umsebenzi we-myostatin. I-Myostatin yiprotheni ebalulekileyo esebenza ukukhusela ukukhula nokuphuhliswa kweeseli zemisipha.

Iimbonakalo:

isebenza ngokubopha i-myostatin kwi-circulation, ukukhusela ukuba ibophe kwi-receptors yayo. La ma-receptors ngokuqhelekileyo asebenza ukuvala ukukhula kwemisipha xa i-myostatin iboshiwe, kodwa ngenxa yokuba i-binding ivalwe yi-ACE-31, ukukhula kwemisipha kunokuqhubeka ngokungapheliyo. Izifundo zezilwanyana kunye nabantu eziyisebenzisayo zibonise ukwanda kobunzima bemisipha kunye nomthamo we-muscle, kunye nemiphumo enenzuzo kwi-fat and bone biomarkers.

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