ICoronavirus ingathelela ama-pericyte, okuyimboni yamakhemikhali yasendaweni ekhiqiza i-SARS-CoV-2.
Lawa ma-SARS-CoV-2 akhiqizwa endaweni angasakazekela kwezinye izinhlobo zamaseli, okudale umonakalo osabalele. Ngalesi simiso semodeli esithuthukisiwe, bathole ukuthi amangqamuzana asekelayo abizwa ngokuthi ama-astrocyte ayizisulu eziyinhloko zalokhu kutheleleka kwesibili.
Imiphumela ikhombisa ukuthi indlela engaba khona yokuthi abakwaSARS-CoV-2 bangene ebuchosheni kungemithambo yegazi, lapho abakwaSARS-CoV-2 bengathelela ama-pericyte, bese kuthi abakwaSARS-CoV-2 basakazekele kwezinye izinhlobo zamangqamuzana obuchopho.
Ama-pericyte angenwe amagciwane angase abangele ukuvuvukala kwemithambo yegazi, okulandelwa ukujiyisa, ukushaywa unhlangothi, noma ukopha. Lezi zinkinga zibonwa ezigulini eziningi ze-SARS-CoV-2 ezingeniswe egunjini labagula kakhulu.
Abacwaningi manje bahlela ukugxila ekuthuthukiseni izinhlanganisela ezithuthukisiwe ezingaqukethe ama-pericyte kuphela, kodwa nemithambo yegazi engakwazi ukupompa igazi ukuze ilingise kangcono ubuchopho bomuntu obuphelele. Ngala mamodeli, singathola ukuqonda okujulile ngezifo ezithathelwanayo nezinye izifo zobuchopho bomuntu.
