Labo abajwayelene nama-peptides bayazi ukuthi i-IGF-1 ingasetshenziselwa umjovo wephuzu-kuya-iphuzu lokukhula kwemisipha yendawo. Ngemva kokuqeqeshwa isikhathi eside, wonke umuntu uzoba namaqembu abo emisipha abuthakathaka, ngakho-ke singakhetha ukusebenzisa indlela yokujova iphuzu-kuya-iphuzu elifana ne-IGF-1 ukuze sifinyelele ukukhula okwanelisayo kwamaqembu emisipha ebuthakathaka.

I-Mechano Growth Factor (MGF). I-Mechano growth Factor (I-Mechano Growth Factor) ifana nenguqulo ethuthukisiwe ye-IGF-1.

Uma sidinga umsipha othize ukuze ukhuliswe endaweni, sishukumisa lowo msipha ngokuzivocavoca kwe-anaerobic okulwa nokumelana, kanye neqembu lemisipha elivuselelwe I-ADAPTS kulokhu kushukumisa ngokuqinisa imicu yemisipha nokwandisa amangqamuzana emisipha. Phakathi nale nqubo, umzimba ukhiqiza i-Mechano Growth Factor ebizwa ngokuthi i-MGF (Mechano Growth Factor). Ngemva ukukhuthazwa mechanical of kwemisipha, IGF-1 isakhi sofuzo iguqulelwa MGF ukuqalisa myohypertrophy futhi kwemisipha fibre division nokulungisa umonakalo imisipha wendawo, okuyinto efezwa kusebenze anabolism of imisipha stem cells. I-MGF ne-IGF-1 empeleni ziyizinto ezingafani, kodwa umehluko wukuthi ukuphela kwe-MGF kune-peptide ye-C-terminal.

Ngakho imisipha esebenzayo empeleni ikhiqiza i-MGF, futhi amaqembu emisipha angasebenzi awakhiqizi i-MGF kuleli phuzu. Qaphela ukuthi i-MGF idlala indima ebalulekile ekukhuleni kwemisipha yendawo.

Ngakho-ke, ukudla okungavamile kwe-MGF mechanical ukukhula kungafeza:

1. Lungisa amangqamuzana emisipha yamathambo awonakele futhi ulungise imicu yemisipha.

2. Nikeza ama-stem cells adingekayo ukuze kukhule imisipha yendawo ukuze kuqinisekiswe ukukhula okwanele kwamaqembu emisipha eqondiwe.

I-MGF isetshenziswe isikhathi eside embonini yokwakha umzimba, futhi umphumela we-TA empeleni usheshayo! Uma yengezwa ngemva kokuqeqeshwa, i-MGF ingakhokhela ngokushesha ukuntuleka kokuqeqeshwa ezindaweni ezihlosiwe noma ukukhula okusheshayo kwamaqembu emisipha anganelisekile.