Semalutide, glucagon zoo li peptide (GLP-1) receptor agonist, tau pom zoo rau kev kho mob ntshav qab zib hom 2. Somaglutide tau tsim los ntawm Novo Nordisk hauv 2012 raws li kev hloov mus sij hawm ntev rau Liraglutide. Piv nrog rau Liraglutide thiab lwm yam tshuaj Ntshav Qab Zib, ib qho ntawm qhov zoo ntawm Somaglutide yog tias nws muaj lub sijhawm ua haujlwm ntev, yog li kev txhaj tshuaj ib zaug ib lim tiam yog txaus. Thaum Lub Kaum Ob Hlis 2017, US Food and Drug Administration (FDA) tau pom zoo rau hom kev txhaj tshuaj ntawm somalutide. Ib qho kev sim tshuaj thib ob yav dhau los pom tias Somaglutide txo qhov hnyav ntawm cov neeg mob ntshav qab zib hom 2 thiab cov neeg rog rog, thiab kev poob phaus tau suav tias yog vim qhov txo qis ntawm lub zog noj los ntawm kev txo qis qab los noj mov.