3D bioprinting bụ teknụzụ nrụpụta dị elu nke nwere ike imepụta ụdị anụ ahụ pụrụ iche na nhazi ya n'ụdị sel etinyere n'ụdị oyi akwa, na-eme ka nhazi a nwee ike igosipụta usoro mkpụrụ ndụ mkpụrụ ndụ dị iche iche nke akụkụ arịa ọbara. Ewebatala usoro hydrogel bio-ink iji chepụta ihe ndị a; Otú ọ dị, inks bio-inks dị nke nwere ike iṅomi nhazi nke arịa ọbara anụ ahụ nwere oke. Inks bio-ink dị ugbu a enweghị nnukwu mbipụta na enweghị ike itinye sel ndụ nwere njupụta dị elu n'ime ụlọ 3D dị mgbagwoju anya, si otú a na-ebelata arụmọrụ ha.

Iji merie adịghị ike ndị a, Gaharwar na Jain mepụtara ọhụrụ nano-engineered bio-ink iji bipụta 3D, arịa ọbara multicellular ziri ezi nke anatomically. Usoro ha na-enye ezigbo mkpebi maka macrostructures na microstructures ọkwa anụ ahụ, nke na-agaghị ekwe omume ugbu a na bio-inks.

Otu ihe pụrụ iche nke nano-engineered bio-ink bụ na n'agbanyeghị njupụta cell, ọ na-egosipụta nnukwu mbipụta na ikike ichekwa sel ndị kpuchiri ekpuchi site n'ikike dị elu n'oge usoro bioprinting. Okwesiri iburu n'uche na 3D bio The cell ebi ebi na-akwado phenotype dị mma ma nọgide na-arụ ọrụ ruo ihe fọrọ nke nta ka ọ bụrụ otu ọnwa ka emechara.

N'iji njirimara ndị a pụrụ iche, nano-engineered bio-inks na-ebipụta n'ime arịa ọbara cylindrical 3D, nke mejupụtara omenala dị ndụ nke mkpụrụ ndụ endothelial na sel anụ ahụ dị nro, nke na-enye ndị na-eme nchọpụta ohere ịmegharị mmetụta nke arịa ọbara na ọrịa.

Nke a 3D bioprinted akpa na-enye ngwá ọrụ nwere ike ịghọta pathophysiology nke vaskụla ọrịa na-enyocha ọgwụgwọ, toxins ma ọ bụ ndị ọzọ kemịkalụ na preclinical ule.