A NA-ekewa ya na ọgwụ POLYPEPTIDE MEDICAL, ọgwụ nje peptide, ogwu ogwu, peptides antimicrobial nke ugbo, nri peptides, ihe ịchọ mma kemịkalụ kwa ụbọchị, peptides SOYBEAN maka nri, peptides ọka, peptides yist, peptides kukumba mmiri.
Site n'echiche ọrụ, enwere ike kewaa ya na peptide antihypertensive, peptide antioxidant, peptide na-ebelata cholesterol, peptide opioid na-arụ ọrụ, nnukwu F-uru oligopeptide, peptide ekpomeekpo na ihe ndị ọzọ.
Peptide na-arụ ọrụ, na-eri nri, hormone, mgbochi enzyme, nhazi nke mgbochi, antibacterial, antiviral, antioxidant nwere mmekọrịta chiri anya. A na-ekekarị peptide n'ime: ọgwụ peptide na ngwaahịa ahụike peptide. Ọgwụ peptide ọdịnala na-abụkarị homonụ peptide. Azụlitewo mmepe nke ọgwụ peptide n'akụkụ dị iche iche nke igbochi ọrịa na ịchịkwa ọrịa, karịsịa na mpaghara ndị a.
Polypeptide mgbochi tumor
Tumorigenesis bụ nsonaazụ nke ọtụtụ ihe, mana n'ikpeazụ gụnyere nhazi nke okwu oncogene. Ọtụtụ mkpụrụ ndụ ihe nketa metụtara tumor na ihe ndị na-achịkwa achọpụtala na 2013. Nleba anya peptides na-ejikọta kpọmkwem na mkpụrụ ndụ ihe nketa ndị a na usoro nchịkwa aghọwo ebe ọhụrụ na-achọ ọgwụ mgbochi ọrịa cancer. Dịka ọmụmaatụ, a na-eji somatostatin agwọ ọrịa etuto endocrine nke usoro nri nri; Ndị nchọpụta America chọtara hexapeptide nke nwere ike igbochi adenocarcinoma nke ọma na vivo; Ndị ọkà mmụta sayensị Switzerland achọpụtala octapeptide nke na-ebute apoptosis n'ime mkpụrụ ndụ tumo.
Antiviral polypeptide
Site na ijikọ ndị na-anabata ya kpọmkwem na sel ndị ọbịa, nje na-agbasa mkpụrụ ndụ ma na-adabere na protease nke onwe ha maka nhazi protein na nucleic acid replication. Ya mere, peptides na-ejikọta ndị na-anabata cell ma ọ bụ saịtị na-arụ ọrụ dị ka nje proteases nwere ike nyochaa site na peptide ọba akwụkwọ maka ọgwụgwọ antiviral. Na 2013, Canada, Italy na mba ndị ọzọ enyochala ọtụtụ obere peptides na ọrịa na-eguzogide site na peptide ọba akwụkwọ, na ụfọdụ n'ime ha abanyela na ogbo nke ụlọ ọgwụ. Na June 2004, Institute of Microbiology, Chinese Academy of Sciences kọrọ na ntụziaka dị mkpa nke ihe ọmụma ọhụrụ oru ngo mere site Institute of Microbiology, Chinese Academy of Sciences, "Research na usoro nke SARS-CoV cell fusion na Fusion inhibitors", nke jikọrọ aka na Institute of Microbiology, Chinese Academy of Sciences and the Center for Modern Virology, Life Sciences, Wuhan University, enweela ọganihu dị ukwuu. Nnwale egosila na peptide HR2 emebere nwere ike igbochi nje virus SARS na-efe efe nke mkpụrụ ndụ mebere nke ọma, yana itinye ihe mgbochi dị mma bụ na mkpokọta ọtụtụ nmoles. Enwekwara ọganihu dị mkpa na nnwale mgbochi mgbochi nje nke synthesized na egosipụtara HR1 peptide na nnwale njikọ in vitro nke HR1 na HR2. Ọgwụ peptide emepụtara iji gbochie njikọ nke nje SARS nwere ike igbochi ọrịa nje na, n'ihe banyere ndị ọrịa butere ọrịa ahụ, gbochie mgbasawanye nke nje na ahụ. Ọgwụ polypeptide nwere ma ọrụ mgbochi na ọgwụgwọ. Ndị na-eme nchọpụta na Centerlọ Ọrụ Nchọpụta Injinịa Cell nke Mahadum Ọgwụ nke anọ ewepụtala peptides itoolu nwere ike igbochi ma gbochie mbuso agha SARS n'ime sel.
Cytokines na-eṅomi peptides
Ojiji nke ndị na-anabata ya maka cytokines a ma ama na-enyocha cytokine mimics si na ụlọ akwụkwọ peptide aghọwo ebe nyocha na 2011. Nyochaa ndị mmadụ na mba ọzọ erythropoietin, ndị mmadụ na-eme ka hormone platelet dịkwuo elu, hormone uto, ihe na-eto eto na-eto eto na ihe dịgasị iche iche nke uto dị ka interleukin - 1 simulation peptide, simulation nke peptide amino acid usoro na ihe sel ya kwekọrọ na ya dị iche, usoro amino acid mana nwere ọrụ cytokines, ma nwee uru nke obere.molekụla arọ. Na 2013 ndị a cytokine na-eṅomi peptides nọ n'okpuru nyocha nke izizi ma ọ bụ ụlọ ọgwụ.
Antibacterial na-arụ ọrụ peptide
Mgbe ụmụ ahụhụ na-akpali site na gburugburu ebe obibi, a na-emepụta ọnụ ọgụgụ buru ibu nke peptides cationic nwere ọrụ antibacterial. N'afọ 2013, enyochala ihe karịrị otu narị ụdị peptides antimicrobial. Nnwale in vitro na in vivo ekwenyela na ọtụtụ peptides antimicrobial ọ bụghị naanị nwere ike antibacterial na nje bacteria, kamakwa ọ nwere ike igbu mkpụrụ ndụ tumo.
Ọgwụ mgbochi peptide
Ọgwụ mgbochi peptide na ọgwụ mgbochi nucleic acid bụ otu n'ime akụkụ kachasị mkpa na nyocha nke ọgwụ mgbochi na 2013. A na-eme ọtụtụ nyocha na mmepe nke ọgwụ nje peptide viral na ụwa na 2013. Dịka ọmụmaatụ, na 1999, NIH bipụtara ya. Nsonaazụ nnwale ụlọọgwụ nke ụdị ọgwụ mgbochi peptide nje HIV-I abụọ n'ihe gbasara mmadụ; A na-enyocha polypeptide site na protein membrane dị n'èzí E2 nke nje ịba ọcha n'anya C (HCV), nke nwere ike ime ka ahụ nwee ike ịmepụta ọgwụ mgbochi. United States na-emepụta ọgwụ mgbochi ọrịa ịba polyvalent antigen polypeptide; Ọgwụ mgbochi peptide papillomavirus mmadụ maka ọrịa kansa cervical abanyela ule ụlọ ọgwụ nke Abụọ. China arụkwara ọtụtụ ọrụ na nyocha nke ọgwụ mgbochi polypeptide dị iche iche.
Peptides maka nyocha
Isi ojiji nke peptides na diagnostic reagents bụ dị ka antigens, ọgwụ mgbochi iji chọpụta ndị kwekọrọ ekwekọ ntule. Polypeptide antigens bụ kpọmkwem karịa microbial ma ọ bụ protein antigens parasitic ma dị mfe ịkwadebe. Ndị na-achọpụta ihe mgbochi mmadụ gbakọtara na polypeptide antigens na 2013 gụnyere: A, B, C, G virus ọrịa imeju, HIV, cytomegalovirus mmadụ, nje herpes simplex, nje rubella, Treponema pallidum, cysticercosis, trypanosoma, ọrịa Lyme na reagents nchọpụta rheumatoid. Ọtụtụ n'ime peptide antigens e ji mee ihe sitere na protein nke ala nke ahụ na-akpata nje kwekọrọ, ụfọdụ bụkwa peptides ọhụrụ enwetara n'ọbá akwụkwọ peptide.
