Tesamorelin peptide (INN) (aha ahia Egrifta) bụ ụdị sịntetịt nke hormone na-ewepụta hormone (GHRH) nke a na-eji na-agwọ ọrịa lipodystrophy metụtara HIV, kwadoro na mbụ na 2010. Ọ bụ Theratechnologies, Inc. nke Canada. Ọgwụ a bụ peptide sịntetik nke mejupụtara amino acid 44 niile nke GHRH mmadụ yana mgbakwunye nke otu trans-3-hexenoic acid.

Tesamorelin peptide bụ analog synthetic synthetic peptide kwụsiri ike nke peptide hypothalamic, Hormone Releasing Hormone (GHRH) egosiputara maka mbelata oke abụba abụba n'ime ndị ọrịa bu nje HIV nwere lipodystrophy. Lipodystrophy bụ ọnọdụ metabolic nke e ji nguzogide insulin, ngbanwe abụba, na hyperlipidemia jikọtara ya na ọgwụgwọ antiretroviral maka nje HIV.

Tesamorelin peptide bụ homonụ na-ewepụta homonụ na-eto eto (GHH) analog nke egosiri na ọ na-abawanye homonụ uto na ọkwa IGF-1. Tesamorelin bụ hormone na-ewepụta GH kacha arụ ọrụ ugbu a n'ahịa. Ọ bụ peptide injectable nke na-ebute mmepụta eke ka ukwuu nke HGH (Homone Growth mmadụ). Ọ na-ejikọta ma na-akpali ndị na-anabata GHRH mmadụ nwere ikike yiri nke GHRH nke anyị. E gosipụtabeghị na ọ na-emetụta oke homonụ pituitary ndị ọzọ na ahụ.

Gland na-akpali akpali: Pituitary Gland

Uru nke TESAMORELIN:

Na-abawanye mmepụta eke nke HGH (hormone uto mmadụ)

Na-abawanye IGF-1 (Insulin Growth Factor - 1) na-agbanweghị oke glucose

Mbelata triglycerides

Mbelata Visceral Adipose Tissue (VAT)

Mbelata mgbasa ozi Carotid Intima (cIMT)

Nghọta nke ọma na ndị okenye karịrị afọ 60.

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