Posachedwapa, Center for Drug Evaluation (CDE) ya State Food and Drug Administration inapereka chidziwitso pa "Technical Guidelines for Pharmaceutical Changes in Marketed Biological Products (Mayeso)". Malangizowo adzakhazikitsidwa kuyambira tsiku lotulutsidwa (June 25, 2021). Lili ndi mitu ya 9 kuphatikizapo mwachidule, mfundo zoyambirira, zofunikira zofunika, kusintha kwa kupanga, kusintha kwa zowonjezera muzitsulo, kusintha kwazomwe zimapangidwira kapena zolembera, kusintha kwa malamulo olembetsa, kusintha kwa zipangizo zonyamula katundu ndi zotengera, kusintha kwa nthawi yovomerezeka kapena kusungirako zinthu. Mfundo zotsogolazi zimagwira ntchito pa zinthu zoteteza zachilengedwe, mankhwala ochizira achilengedwe, ndi zida zowunikira mu m'galasi zomwe zimayendetsedwa ndi zinthu zachilengedwe, ndikufotokozeranso malingaliro oyambira ndi nkhawa za kafukufuku wokhudza kusintha kalembera ndi kasamalidwe kazinthu zachilengedwe msika ukatha.